Lorna Brown
She/Her
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About
Research Topic:
Circadian rhythms and ageing
Qualifications:
MSc Biological Sciences by Research, Royal Holloway University of London
BSc Biomedical Science, Royal Holloway University of London
Research interests
Circadian rhythms (biological oscillations of approximately 24 hrs) regulate many daily physiological and behavioural processes including the sleep-wake cycle, hormone release, and rest-activity rhythms. Therefore, circadian rhythms play an important role in our overall health. However, many factors including ageing, lifestyle choices (e.g., increased nighttime use of electronic devices), and disease’s (such as Alzheimer’s disease) result in disruption to circadian rhythmicity. Thus, negatively influencing a variety of biological processes and in turn our health.
Supervision
Supervisors: Dr Aiste Steponenaite, Professor Gurprit Lall
Research Group: Biological Sciences
Publications:
Steponenaite, A., Lalic, T., Atkinson, L., Tanday, N., Brown, L., Mathie, A., Cader, Z. M., Lall, G. S. (2024). TASK-3, two-pore potassium channels, contribute to circadian rhythms in the electrical properties of the suprachiasmatic nucleus and play a role in driving stable behavioural photic entrainment. Chronobiology International, 41(6), 802–816. https://doi.org/10.1080/07420528.2024.2351515