Portrait of Dr Jamie Chien-Ming Hsieh

Dr Jamie Chien-Ming Hsieh

He/Him

Lecturer Pharmaceutics and Drug Delivery

About

Dr. Jamie Chien-Ming Hsieh, a registered pharmacist, holds a Bachelor of Science in Pharmacy from Taipei Medical University and a PhD in Pharmaceutical Science from King’s College London. Prior to his appointment at the Medway School of Pharmacy, Dr. Hsieh served as an Honorary Research Fellow at University College London (UCL) and as a Professor at the School of Pharmacy, Taipei Medical University, Taiwan.

 

Dr. Hsieh’s research focuses on the development of advanced drug delivery systems for low molecular weight therapeutics and biomolecules, including the design and optimization of both novel and conventional surfactant-, polymer-, and lipid-based platforms. His contributions to the field of drug delivery have been recognized through numerous publications in high-impact, peer-reviewed journals, including the International Journal of Nanomedicine, Biomedicine & Pharmacotherapy, and Carbohydrate Polymers.

 

Dr. Hsieh maintains active research collaborations with leading academic institutions across the UK, including King’s College London, the University of Manchester, and University College London. These collaborations integrate physiologically-based pharmacokinetic (PBPK) modeling to facilitate the clinical translation of nanomedicine platforms, with the overarching goal of advancing innovative therapeutic solutions.

 

Specialist areas:

Pharmaceutical Science, Pharmacokinetics, Drug Delivery Systems, Nanomedicine, PBPK modelling

Research interests

Dr. Hsieh’s research focuses on the development of advanced drug delivery systems for low molecular weight therapeutics and biomolecules, including DNA and siRNA, through a comprehensive investigation of the physicochemical properties of nanocarriers. His work systematically examines the interplay between molecular structure, nanocarrier architecture, stability, and intracellular dynamics, providing a robust scientific foundation for optimizing their performance and therapeutic efficacy within target cells.

Dr. Hsieh’s current research focuses on integrating physiologically-based pharmacokinetic (PBPK) modelling to inform the design and accelerate the clinical translation of nanomedicine systems. This modeling approach enables the precise prediction of drug distribution, metabolism, and therapeutic efficacy in vivo, with a particular focus on advancing delivery strategies optimized for pulmonary applications. By combining molecular design, structural characterization, and translational modeling, Dr. Hsieh aims to elucidate the mechanistic determinants of delivery vehicle performance, ultimately enhancing their biological efficacy and clinical applicability.

Teaching

Dr. Hsieh teaches pharmaceutics across all four stages of the MPharm programme.

Supervision

I welcome self-funded PhD students with an ininterest in nanomedicine and pharmacokinetic modelling research to reach out regarding potential opportunities to work on research projects.

Professional

Memberships of editorial boards and professional bodies.
• Member of the Royal Society of Chemistry (MRSC)
• Member of the Controlled Release Society (CRS)
• Member of the International Society for the Study of Xenobiotics (ISSX)

Last updated 20th January 2025