Dr Jamie Chien-Ming Hsieh
He/Him
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About
| Dr. Jamie Chien-Ming Hsieh is a registered pharmacist who obtained his Bachelor of Science in Pharmacy from Taipei Medical University and his PhD in Pharmaceutical Science from King’s College London.
Dr. Hsieh’s research focuses on the development of advanced drug delivery systems for both low molecular weight therapeutics and biomacromolecules. His work encompasses the design, formulation, and optimisation of novel and conventional delivery platforms based on surfactants, polymers, and lipids. His contributions to the field have been recognised through publications in leading peer-reviewed journals, including the International Journal of Nanomedicine, Biomedicine & Pharmacotherapy, and Carbohydrate Polymers.
Dr. Hsieh maintains active research collaborations with several leading academic institutions across the United Kingdom, including King’s College London, the University of Manchester, and University College London. These collaborations integrate physiologically based pharmacokinetic (PBPK) modelling to facilitate the clinical translation of nanomedicine platforms, with the overarching aim of advancing innovative therapeutic strategies. He has also held the position of Honorary Research Fellow at University College London.
Specialist areas: Pharmaceutical Science, Pharmacokinetics, Drug Delivery Systems, Nanomedicine, PBPK modelling |
Research interests
Dr Hsieh’s research focuses on developing advanced drug delivery systems for low-molecular-weight therapeutics and biomolecules, including DNA and siRNA. His work explores the relationships between molecular structure, nanocarrier design, stability, and intracellular behaviour to optimise delivery efficiency and therapeutic outcomes. He currently integrates physiologically based pharmacokinetic (PBPK) modelling to guide the design and clinical translation of nanomedicine platforms, with a particular emphasis on pulmonary delivery. He applies neutron scattering techniques to characterise the structural properties of lipid nanoparticle (LNP) systems across different formulations and to monitor their stability during nebulisation, aiming to optimise LNPs for inhaled RNA therapies in patients with chronic lung conditions. By combining molecular design, structural analysis, and translational modelling, Dr Hsieh seeks to enhance the efficacy and clinical applicability of next-generation drug delivery systems.
Teaching
Dr. Hsieh teaches pharmaceutics across all four stages of the MPharm programme.
Supervision
I welcome self-funded PhD students with an ininterest in nanomedicine and pharmacokinetic modelling research to reach out regarding potential opportunities to work on research projects.
Professional
Memberships of editorial boards and professional bodies.
• Member of the Royal Society of Chemistry (MRSC)
• Member of the Controlled Release Society (CRS)
• Member of the International Society for the Study of Xenobiotics (ISSX)